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Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes

BACKGROUND: The spatial organization of the mammalian genome relies upon the formation of chromatin domains of various scales. At the level of gene regulation in cis, collections of enhancer sequences define large regulatory landscapes that usually match with the presence of topologically associatin...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Rodríguez-Carballo, Eddie, Lopez-Delisle, Lucille, Yakushiji-Kaminatsui, Nayuta, Ullate-Agote, Asier, Duboule, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626364/
https://ncbi.nlm.nih.gov/pubmed/31299961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-019-0677-x
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