A behavior-based drug screening system using a Caenorhabditis elegans model of motor neuron disease

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons, for which there is no effective treatment. Previously, we generated a Caenorhabditis elegans model of ALS, in which the expression of dnc-1, the homologous gene of human d...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ikenaka, Kensuke, Tsukada, Yuki, Giles, Andrew C., Arai, Tadamasa, Nakadera, Yasuhito, Nakano, Shunji, Kawai, Kaori, Mochizuki, Hideki, Katsuno, Masahisa, Sobue, Gen, Mori, Ikue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626054/
https://ncbi.nlm.nih.gov/pubmed/31300701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46642-6
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge