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Poly(ADP-ribosylation) in age-related neurological disease

A central and causative feature of age-related neurodegenerative disease is the deposition of misfolded proteins in the brain. To devise novel approaches to treatment, regulatory pathways that modulate these aggregation-prone proteins must be defined. One such pathway is the post-translational modif...

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Detalhes bibliográficos
Publicado no:Trends Genet
Main Authors: McGurk, Leeanne, Rifai, Olivia M., Bonini, Nancy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625889/
https://ncbi.nlm.nih.gov/pubmed/31182245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2019.05.004
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