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N-glycan-calnexin interactions in human factor VII secretion and deficiency

Factor VII (FVII) is a key serine protease in blood coagulation. N-glycosylation in FVII has been shown to be critical for protein secretion. To date, however, the underlying biochemical mechanism remains unclear. Recently, we found that N-glycans in the transmembrane serine protease corin are criti...

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Publicat a:Int J Biochem Cell Biol
Autors principals: Wang, Hao, Wang, Lina, Li, Shuo, Dong, Ningzheng, Wu, Qingyu
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625852/
https://ncbi.nlm.nih.gov/pubmed/31185295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2019.05.017
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