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N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding

Trypsin-like serine proteases are essential in physiological processes. Studies have shown that N-glycans are important for serine protease expression and secretion, but the underlying mechanisms are poorly understood. Here, we report a common mechanism of N-glycosylation in the protease domains of...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Wang, Hao, Li, Shuo, Wang, Juejin, Chen, Shenghan, Sun, Xue-Long, Wu, Qingyu
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021170/
https://ncbi.nlm.nih.gov/pubmed/29889025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35672
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