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Oxetane-Based Polyketide Surrogate To Probe Substrate Binding in a Polyketide Synthase
Polyketides are a large class of bioactive natural products with a wide range of structures and functions. Polyketides are biosynthesized by large, multi-domain enzyme complexes termed polyketide synthases (PKSs). One of the primary challenges when studying PKSs is the high reactivity of their poly-...
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| 出版年: | J Am Chem Soc |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6625825/ https://ncbi.nlm.nih.gov/pubmed/29620883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11793 |
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