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Prion-like mechanisms in Parkinson Disease

Over 100 years ago, Lewy bodies and Lewy neurites were defined as a pathological hallmark of Parkinson’s disease. Eighty years later, α-synuclein was found to be the primary component of these inclusions. Emerging evidence suggests that α-synuclein pathology propagates across interconnected networks...

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Publicat a:Handb Clin Neurol
Autors principals: Volpicelli-Daley, Laura, Brundin, Patrik
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625652/
https://ncbi.nlm.nih.gov/pubmed/29887143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-444-63945-5.00017-9
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