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Ester derived titanium enolate aldol reaction: chelation controlled diastereoselective synthesis of syn-aldols

A chelation controlled and highly diastereoselective synthesis of syn-aldols is described. Aldol reaction of commercially available L-phenylalaninol derived esters with a variety of bidentate oxyaldehydes proceeded with excellent syn-diastereoselectivities and isolated yields.

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Detalhes bibliográficos
Publicado no:Tetrahedron Lett
Main Authors: Ghosh, Arun K., Kim, Jae-Hun
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625521/
https://ncbi.nlm.nih.gov/pubmed/31303686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0040-4039(00)02227-9
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