ロード中...

High-Affinity Bent β(2)-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis

Leukocyte adhesion requires β(2)-integrin activation. Resting integrins exist in a bent-closed conformation—i.e., not extended (E(−)) and not high affinity (H(−))—unable to bind ligand. Fully activated E(+)H(+) integrin binds intercellular adhesion molecules (ICAMs) expressed on the opposing cell in...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Fan, Zhichao, Kiosses, William Bill, Sun, Hao, Orecchioni, Marco, Ghosheh, Yanal, Zajonc, Dirk M., Arnaout, M. Amin, Gutierrez, Edgar, Groisman, Alex, Ginsberg, Mark H., Ley, Klaus
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625519/
https://ncbi.nlm.nih.gov/pubmed/30605669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.12.038
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!