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The molecular rationale for therapeutic targeting of glutamine metabolism in pulmonary hypertension
INTRODUCTION: Pulmonary hypertension (PH) is a deadly enigmatic disease with increasing prevalence. Cellular pathologic hallmarks of PH are driven at least partly by metabolic rewiring, but details are just emerging. The discovery that vascular matrix stiffening can mechanically activate the glutami...
שמור ב:
| הוצא לאור ב: | Expert Opin Ther Targets |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6625322/ https://ncbi.nlm.nih.gov/pubmed/31055988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2019.1615438 |
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