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Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains

Pulmonary hypertension (PH) is a heterogeneous and fatal disease of the lung vasculature, where metabolic and mitochondrial dysfunction may drive pathogenesis. Similar to the Warburg effect in cancer, a shift from mitochondrial oxidation to glycolysis occurs in diseased pulmonary vessels and the rig...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Culley, Miranda K., Chan, Stephen Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118596/
https://ncbi.nlm.nih.gov/pubmed/30080181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120847
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