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Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains
Pulmonary hypertension (PH) is a heterogeneous and fatal disease of the lung vasculature, where metabolic and mitochondrial dysfunction may drive pathogenesis. Similar to the Warburg effect in cancer, a shift from mitochondrial oxidation to glycolysis occurs in diseased pulmonary vessels and the rig...
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| Gepubliceerd in: | J Clin Invest |
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| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6118596/ https://ncbi.nlm.nih.gov/pubmed/30080181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120847 |
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