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Diabetes Relief in Mice by Glucose-Sensing Insulin-Secreting Human α-Cells

Cell identity switches, where terminally-differentiated cells convert into different cell-types when stressed, represent a widespread regenerative strategy in animals, yet they are poorly documented in mammals. In mice, some glucagon-producing pancreatic α-cells and somatostatin-producing δ-cells be...

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Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Furuyama, Kenichiro, Chera, Simona, van Gurp, Léon, Oropeza, Daniel, Ghila, Luiza, Damond, Nicolas, Vethe, Heidrun, Paulo, Joao A., Joosten, Antoinette M., Berney, Thierry, Bosco, Domenico, Dorrell, Craig, Grompe, Markus, Ræder, Helge, Roep, Bart O., Thorel, Fabrizio, Herrera, Pedro L.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624841/
https://ncbi.nlm.nih.gov/pubmed/30760930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-0942-8
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