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Treatment for Preventing Tuberculosis in Children and Adolescents: A Randomized Clinical Trial of a 3-Month, 12-Dose Regimen of a Combination of Rifapentine and Isoniazid

IMPORTANCE: Three months of a once-weekly combination of rifapentine and isoniazid for treatment of latent tuberculosis infection is safe and effective for persons 12 years or older. Published data for children are limited. OBJECTIVES: To compare treatment safety and assess noninferiority treatment...

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Detalhes bibliográficos
Publicado no:JAMA Pediatr
Main Authors: Villarino, M. Elsa, Scott, Nigel A., Weis, Stephen E., Weiner, Marc, Conde, Marcus B., Jones, Brenda, Nachman, Sharon, Oliveira, Ricardo, Moro, Ruth N., Shang, Nong, Goldberg, Stefan V., Sterling, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624831/
https://ncbi.nlm.nih.gov/pubmed/25580725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapediatrics.2014.3158
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