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Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis

BACKGROUND: Rifapentine-based regimens have potent antimycobacterial activity that may allow for a shorter course in patients with drug-susceptible pulmonary tuberculosis. METHODS: In an open-label, phase 3, randomized, controlled trial involving persons with newly diagnosed pulmonary tuberculosis f...

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Veröffentlicht in:N Engl J Med
Hauptverfasser: Dorman, Susan E., Nahid, Payam, Kurbatova, Ekaterina V., Phillips, Patrick P.J., Bryant, Kia, Dooley, Kelly E., Engle, Melissa, Goldberg, Stefan V., Phan, Ha T.T., Hakim, James, Johnson, John L., Lourens, Madeleine, Martinson, Neil A., Muzanyi, Grace, Narunsky, Kim, Nerette, Sandy, Nguyen, Nhung V., Pham, Thuong H., Pierre, Samuel, Purfield, Anne E., Samaneka, Wadzanai, Savic, Radojka M., Sanne, Ian, Scott, Nigel A., Shenje, Justin, Sizemore, Erin, Vernon, Andrew, Waja, Ziyaad, Weiner, Marc, Swindells, Susan, Chaisson, Richard E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282329/
https://ncbi.nlm.nih.gov/pubmed/33951360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa2033400
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