Methadone and buprenorphine pharmacokinetics and pharmacodynamics when coadministered with fostemsavir to opioid‐dependent, human immunodeficiency virus seronegative participants

AIMS: Regional human immunodeficiency virus (HIV) prevalence rates are high in people with history of injection drug use, including those managed with maintenance opioids. Fostemsavir (FTR) is an oral prodrug of temsavir, a first‐in‐class attachment inhibitor that binds HIV‐1 gp120, preventing initi...

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Bibliographic Details
Published in:Br J Clin Pharmacol
Main Authors: Moore, Katy, Magee, Mindy, Sevinsky, Heather, Chang, Ming, Lubin, Susan, Myers, Elsa, Ackerman, Peter, Llamoso, Cyril
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624406/
https://ncbi.nlm.nih.gov/pubmed/30980734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13964
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