NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region

Faithful transcription initiation is critical for accurate gene expression, yet the mechanisms underlying specific transcription start site (TSS) selection in mammals remain unclear. Here, we show that the histone-fold domain protein NF-Y, a ubiquitously expressed transcription factor, controls the...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Oldfield, Andrew J., Henriques, Telmo, Kumar, Dhirendra, Burkholder, Adam B., Cinghu, Senthilkumar, Paulet, Damien, Bennett, Brian D., Yang, Pengyi, Scruggs, Benjamin S., Lavender, Christopher A., Rivals, Eric, Adelman, Karen, Jothi, Raja
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624317/
https://ncbi.nlm.nih.gov/pubmed/31296853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10905-7
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