Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity

Histone H3 lysine 36 methylation (H3K36me) is thought to participate in a host of co-transcriptional regulatory events. To study the function of this residue independent from the enzymes that modify it, we used a ‘histone replacement’ system in Drosophila to generate a non-modifiable H3K36 lysine-to...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Meers, Michael P, Henriques, Telmo, Lavender, Christopher A, McKay, Daniel J, Strahl, Brian D, Duronio, Robert J, Adelman, Karen, Matera, A Gregory
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2017
Ämnen:
Genes and Chromosomes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404926/
https://ncbi.nlm.nih.gov/pubmed/28346137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23249
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