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cPLA2 activation contributes to lysosomal defects leading to impairment of autophagy after spinal cord injury

The autophagy–lysosomal pathway plays an essential role in cellular homeostasis as well as a protective function against a variety of diseases including neurodegeneration. Conversely, inhibition of autophagy, for example due to lysosomal dysfunction, can lead to pathological accumulation of dysfunct...

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Li, Yun, Jones, Jace W., M. C. Choi, Harry, Sarkar, Chinmoy, Kane, Maureen A., Koh, Eugene Y., Lipinski, Marta M., Wu, Junfang
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624263/
https://ncbi.nlm.nih.gov/pubmed/31296844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1764-1
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