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cPLA2 activation contributes to lysosomal defects leading to impairment of autophagy after spinal cord injury
The autophagy–lysosomal pathway plays an essential role in cellular homeostasis as well as a protective function against a variety of diseases including neurodegeneration. Conversely, inhibition of autophagy, for example due to lysosomal dysfunction, can lead to pathological accumulation of dysfunct...
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| Pubblicato in: | Cell Death Dis |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6624263/ https://ncbi.nlm.nih.gov/pubmed/31296844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1764-1 |
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