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Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells

Lipid-induced toxicity is part of several human diseases, but the mechanisms involved are not fully understood. Fatty liver is characterized by the expression of different growth and tissue factors. The neurotrophin, nerve growth factor (NGF) and its pro-form, pro-NGF, are present in fatty liver tog...

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Publicado en:Cell Death Dis
Autores principales: Pham, Dan Duc, Bruelle, Céline, Thi Do, Hai, Pajanoja, Ceren, Jin, Congyu, Srinivasan, Vignesh, Olkkonen, Vesa M., Eriksson, Ove, Jauhiainen, Matti, Lalowski, Maciej, Lindholm, Dan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624261/
https://ncbi.nlm.nih.gov/pubmed/31296846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1758-z
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