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Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells

Lipid-induced toxicity is part of several human diseases, but the mechanisms involved are not fully understood. Fatty liver is characterized by the expression of different growth and tissue factors. The neurotrophin, nerve growth factor (NGF) and its pro-form, pro-NGF, are present in fatty liver tog...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Pham, Dan Duc, Bruelle, Céline, Thi Do, Hai, Pajanoja, Ceren, Jin, Congyu, Srinivasan, Vignesh, Olkkonen, Vesa M., Eriksson, Ove, Jauhiainen, Matti, Lalowski, Maciej, Lindholm, Dan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624261/
https://ncbi.nlm.nih.gov/pubmed/31296846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1758-z
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