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Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein
Most neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) target the receptor-binding domain (RBD) of the spike glycoprotein and block its binding to the cellular receptor dipeptidyl peptidase 4 (DPP4). The epitopes and mechanisms of mAbs targeting non-RBD regions...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6624210/ https://ncbi.nlm.nih.gov/pubmed/31296843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10897-4 |
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