Pathway analysis of rare variants for the clustered phenotypes by using hierarchical structured components analysis

BACKGROUNDS: Recent large-scale genetic studies often involve clustered phenotypes such as repeated measurements. Compared to a series of univariate analyses of single phenotypes, an analysis of clustered phenotypes can be useful for substantially increasing statistical power to detect more genetic...

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Vydáno v:BMC Med Genomics
Hlavní autoři: Lee, Sungyoung, Kim, Sunmee, Kim, Yongkang, Oh, Bermseok, Hwang, Heungsun, Park, Taesung
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624181/
https://ncbi.nlm.nih.gov/pubmed/31296220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0517-4
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