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Dynamic genetic regulation of gene expression during cellular differentiation

Genetic regulation of gene expression is dynamic, as transcription can change during cell differentiation and across cell types. We mapped expression quantitative trait loci (eQTLs) throughout differentiation to elucidate the dynamics of genetic effects on cell type specific gene expression. We gene...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Strober, B.J., Elorbany, R., Rhodes, K., Krishnan, N., Tayeb, K., Battle, A., Gilad, Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623972/
https://ncbi.nlm.nih.gov/pubmed/31249060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw0040
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