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Differential regulation of Tbx5 protein expression and sub-cellular localization during heart development
The T-box transcription factor Tbx5 can interact with Nkx2.5 and Gata4 transcription factors to synergistically regulate heart-specific genes in the nucleus. While a nuclear role for Tbx5 is clearly defined, we have previously shown that Tbx5 shuttles from nuclear to cytoplasmic sites, forming a com...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876776/ https://ncbi.nlm.nih.gov/pubmed/17045582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.09.023 |
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