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Differential regulation of Tbx5 protein expression and sub-cellular localization during heart development

The T-box transcription factor Tbx5 can interact with Nkx2.5 and Gata4 transcription factors to synergistically regulate heart-specific genes in the nucleus. While a nuclear role for Tbx5 is clearly defined, we have previously shown that Tbx5 shuttles from nuclear to cytoplasmic sites, forming a com...

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Detalhes bibliográficos
Main Authors: Bimber, Benjamin, Dettman, Robert W., Simon, Hans-Georg
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876776/
https://ncbi.nlm.nih.gov/pubmed/17045582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.09.023
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