Promotion of Non-Rapid Eye Movement Sleep and Activation of Reticular Thalamic Neurons by a Novel MT(2) Melatonin Receptor Ligand

Melatonin activates two brain G-protein coupled receptors, MT(1) and MT(2), whose differential roles in the sleep–wake cycle remain to be defined. The novel MT(2) receptor partial agonist, N-{2-[(3-methoxyphenyl) phenylamino] ethyl} acetamide (UCM765), is here shown to selectively promote non-rapid...

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Publicat a:J Neurosci
Autors principals: Ochoa-Sanchez, Rafael, Comai, Stefano, Lacoste, Baptiste, Bambico, Francis Rodriguez, Dominguez-Lopez, Sergio, Spadoni, Gilberto, Rivara, Silvia, Bedini, Annalida, Angeloni, Debora, Fraschini, Franco, Mor, Marco, Tarzia, Giorgio, Descarries, Laurent, Gobbi, Gabriella
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623882/
https://ncbi.nlm.nih.gov/pubmed/22171046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2676-11.2011
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