The Distinct Role of Medium Spiny Neurons and Cholinergic Interneurons in the D(2)/A(2A) Receptor Interaction in the Striatum: Implications for Parkinson's Disease

A(2A) adenosine receptor antagonists are currently under investigation as potential therapeutic agents for Parkinson's disease (PD). However, the molecular mechanisms underlying this therapeutic effect is still unclear. A functional antagonism exists between A(2A) adenosine and D(2) dopamine (D...

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Pubblicato in:J Neurosci
Autori principali: Tozzi, Alessandro, de Iure, Antonio, Di Filippo, Massimiliano, Tantucci, Michela, Costa, Cinzia, Borsini, Franco, Ghiglieri, Veronica, Giampà, Carmen, Fusco, Francesca Romana, Picconi, Barbara, Calabresi, Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623738/
https://ncbi.nlm.nih.gov/pubmed/21289195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4082-10.2011
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