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Mitochondrial DNA Damage Level Determines Neural Stem Cell Differentiation Fate
The mitochondrial DNA (mtDNA) of neural stem cells (NSCs) is vulnerable to oxidation damage. Subtle manipulations of the cellular redox state affect mtDNA integrity in addition to regulating the NSC differentiation lineage, suggesting a molecular link between mtDNA integrity and regulation of differ...
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| Veröffentlicht in: | J Neurosci |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6623160/ https://ncbi.nlm.nih.gov/pubmed/21715639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0852-11.2011 |
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