Mitochondrial DNA Damage Level Determines Neural Stem Cell Differentiation Fate

The mitochondrial DNA (mtDNA) of neural stem cells (NSCs) is vulnerable to oxidation damage. Subtle manipulations of the cellular redox state affect mtDNA integrity in addition to regulating the NSC differentiation lineage, suggesting a molecular link between mtDNA integrity and regulation of differ...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Wang, Wei, Esbensen, Ying, Kunke, David, Suganthan, Rajikala, Rachek, Lyudmila, Bjørås, Magnar, Eide, Lars
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2011
Onderwerpen:
Brief Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623160/
https://ncbi.nlm.nih.gov/pubmed/21715639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0852-11.2011
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