Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism

OBJECTIVE: In the adult brain, neural stem cells (NSCs) located in the subventricular zone (SVZ) produce both neuronal and glial cells. Thyroid hormones (THs) regulate adult NSC differentiation towards a neuronal phenotype, but also have major roles in mitochondrial metabolism. As NSC metabolism rel...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Gothié, J.D., Sébillot, A., Luongo, C., Legendre, M., Nguyen Van, C., Le Blay, K., Perret-Jeanneret, M., Remaud, S., Demeneix, B.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681236/
https://ncbi.nlm.nih.gov/pubmed/29107300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.08.003
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