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ClC-2 Channels Regulate Neuronal Excitability, Not Intracellular Chloride Levels
Synaptic inhibition by GABA(A) receptors requires a transmembrane chloride gradient. Hyperpolarization or shunting results from outward current produced by chloride flowing down this gradient, into the cell. Chloride influx necessarily depletes the chloride gradient. Therefore, mechanisms that reple...
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| 出版年: | J Neurosci |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6623024/ https://ncbi.nlm.nih.gov/pubmed/22049427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2748-11.2011 |
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