The Neural Cell Adhesion Molecule Promotes FGFR-Dependent Phosphorylation and Membrane Targeting of the Exocyst Complex to Induce Exocytosis in Growth Cones

The exocyst complex is an essential regulator of polarized exocytosis involved in morphogenesis of neurons. We show that this complex binds to the intracellular domain of the neural cell adhesion molecule (NCAM). NCAM promotes FGF receptor-mediated phosphorylation of two tyrosine residues in the sec...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Chernyshova, Yana, Leshchyns'ka, Iryna, Hsu, Shu-Chan, Schachner, Melitta, Sytnyk, Vladimir
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2011
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622784/
https://ncbi.nlm.nih.gov/pubmed/21389209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3109-10.2011
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