Depolarizing Actions of GABA in Immature Neurons Depend Neither on Ketone Bodies Nor on Pyruvate

GABA depolarizes immature neurons because of a high [Cl(−)](i) and orchestrates giant depolarizing potential (GDP) generation. Zilberter and coworkers (Rheims et al., 2009; Holmgren et al., 2010) showed recently that the ketone body metabolite dl-3-hydroxybutyrate (dl-BHB) (4 mm), lactate (4 mm), or...

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Publicado no:J Neurosci
Main Authors: Tyzio, Roman, Allene, Camille, Nardou, Romain, Picardo, Michel A., Yamamoto, Sumii, Sivakumaran, Sudhir, Caiati, Maddalena D., Rheims, Sylvain, Minlebaev, Marat, Milh, Mathieu, Ferré, Pascal, Khazipov, Rustem, Romette, Jean-Louis, Lorquin, Jean, Cossart, Rosa, Khalilov, Ilgam, Nehlig, Astrid, Cherubini, Enrico, Ben-Ari, Yehezkel
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622726/
https://ncbi.nlm.nih.gov/pubmed/21209187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3314-10.2011
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