Epileptiform Activity Induces Vascular Remodeling and Zonula Occludens 1 Downregulation in Organotypic Hippocampal Cultures: Role of VEGF Signaling Pathways

Recent studies suggest that blood–brain barrier (BBB) permeability contributes to epileptogenesis in symptomatic epilepsies. We have previously described angiogenesis, aberrant vascularization, and BBB alteration in drug-refractory temporal lobe epilepsy. Here, we investigated the role of vascular e...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Morin-Brureau, Mélanie, Lebrun, Aurore, Rousset, Marie-Claude, Fagni, Laurent, Bockaert, Joël, de Bock, Frédéric, Lerner-Natoli, Mireille
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622643/
https://ncbi.nlm.nih.gov/pubmed/21775611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5692-10.2011
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