Epileptiform Activity Induces Vascular Remodeling and Zonula Occludens 1 Downregulation in Organotypic Hippocampal Cultures: Role of VEGF Signaling Pathways

Recent studies suggest that blood–brain barrier (BBB) permeability contributes to epileptogenesis in symptomatic epilepsies. We have previously described angiogenesis, aberrant vascularization, and BBB alteration in drug-refractory temporal lobe epilepsy. Here, we investigated the role of vascular e...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Morin-Brureau, Mélanie, Lebrun, Aurore, Rousset, Marie-Claude, Fagni, Laurent, Bockaert, Joël, de Bock, Frédéric, Lerner-Natoli, Mireille
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2011
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622643/
https://ncbi.nlm.nih.gov/pubmed/21775611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5692-10.2011
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