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Epileptiform Activity Induces Vascular Remodeling and Zonula Occludens 1 Downregulation in Organotypic Hippocampal Cultures: Role of VEGF Signaling Pathways

Recent studies suggest that blood–brain barrier (BBB) permeability contributes to epileptogenesis in symptomatic epilepsies. We have previously described angiogenesis, aberrant vascularization, and BBB alteration in drug-refractory temporal lobe epilepsy. Here, we investigated the role of vascular e...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Morin-Brureau, Mélanie, Lebrun, Aurore, Rousset, Marie-Claude, Fagni, Laurent, Bockaert, Joël, de Bock, Frédéric, Lerner-Natoli, Mireille
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622643/
https://ncbi.nlm.nih.gov/pubmed/21775611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5692-10.2011
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