Synapsin I Is an Oligomannose-Carrying Glycoprotein, Acts As an Oligomannose-Binding Lectin, and Promotes Neurite Outgrowth and Neuronal Survival When Released via Glia-Derived Exosomes

Oligomannosidic glycans play important roles in nervous system development and function. By performing a phage display screening with oligomannose-specific antibodies, we identified an oligomannose-mimicking peptide that was functionally active in modulating neurite outgrowth and neuron–astrocyte ad...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Wang, Shiwei, Cesca, Fabrizia, Loers, Gabriele, Schweizer, Michaela, Buck, Friedrich, Benfenati, Fabio, Schachner, Melitta, Kleene, Ralf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622588/
https://ncbi.nlm.nih.gov/pubmed/21593312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6476-10.2011
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