2-Cl-C.OXT-A stimulates contraction through the suppression of phosphodiesterase activity in human induced pluripotent stem cell-derived cardiac organoids

BACKGROUND: 2-Cl-C.OXT-A (COA-Cl) is a novel synthesized adenosine analog that activates Sphingosine-1-phosphate 1 receptor (S1P1R) and combines with the adenosine A1 receptor (A1R) in G proteins and was shown to enhance angiogenesis and improve the brain function in rat stroke models. However, the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Kitsuka, Takahiro, Itoh, Manabu, Amamoto, Sojiro, Arai, Ken-ichi, Oyama, Junichi, Node, Koichi, Toda, Shuji, Morita, Shigeki, Nishida, Takahiro, Nakayama, Koichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622471/
https://ncbi.nlm.nih.gov/pubmed/31295264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213114
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge