Lipidomics Detection of Brain Cardiolipins in Plasma Is Associated with Outcome after Cardiac Arrest

OBJECTIVE: Brain mitochondrial dysfunction limits neurological recovery after cardiac arrest (CA). Brain polyunsaturated cardiolipins (CLs), mitochondria-unique and functionally essential phospholipids, have unprecedented diversification. Since brain CLs are not present in plasma normally, we hypoth...

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Detalhes bibliográficos
Publicado no:Crit Care Med
Main Authors: Anthonymuthu, Tamil S., Kenny, Elizabeth M., Lamade, Andrew M., Gidwani, Hitesh, Krehel, Nicholas M., Misse, Amalea, Gao, Xiaotian, Amoscato, Andrew A., Straub, Adam C., Kagan, Valerian E., Dezfulian, Cameron, BayIr, Hülya
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622168/
https://ncbi.nlm.nih.gov/pubmed/30855329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000003636
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