Lipidomics Detection of Brain Cardiolipins in Plasma Is Associated with Outcome after Cardiac Arrest

OBJECTIVE: Brain mitochondrial dysfunction limits neurological recovery after cardiac arrest (CA). Brain polyunsaturated cardiolipins (CLs), mitochondria-unique and functionally essential phospholipids, have unprecedented diversification. Since brain CLs are not present in plasma normally, we hypoth...

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Bibliografske podrobnosti
izdano v:Crit Care Med
Main Authors: Anthonymuthu, Tamil S., Kenny, Elizabeth M., Lamade, Andrew M., Gidwani, Hitesh, Krehel, Nicholas M., Misse, Amalea, Gao, Xiaotian, Amoscato, Andrew A., Straub, Adam C., Kagan, Valerian E., Dezfulian, Cameron, BayIr, Hülya
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622168/
https://ncbi.nlm.nih.gov/pubmed/30855329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000003636
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