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Evolutionary couplings detect side-chain interactions

Patterns of amino acid covariation in large protein sequence alignments can inform the prediction of de novo protein structures, binding interfaces, and mutational effects. While algorithms that detect these so-called evolutionary couplings between residues have proven useful for practical applicati...

詳細記述

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書誌詳細
出版年:PeerJ
主要な著者: Hockenberry, Adam J., Wilke, Claus O.
フォーマット: Artigo
言語:Inglês
出版事項: PeerJ Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622159/
https://ncbi.nlm.nih.gov/pubmed/31328041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.7280
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