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Phylogenetic Weighting Does Little to Improve the Accuracy of Evolutionary Coupling Analyses

Homologous sequence alignments contain important information about the constraints that shape protein family evolution. Correlated changes between different residues, for instance, can be highly predictive of physical contacts within three-dimensional structures. Detecting such co-evolutionary signa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Entropy (Basel)
Egile Nagusiak: Hockenberry, Adam J., Wilke, Claus O.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818970/
https://ncbi.nlm.nih.gov/pubmed/31662602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/e21101000
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