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Phylogenetic Weighting Does Little to Improve the Accuracy of Evolutionary Coupling Analyses

Homologous sequence alignments contain important information about the constraints that shape protein family evolution. Correlated changes between different residues, for instance, can be highly predictive of physical contacts within three-dimensional structures. Detecting such co-evolutionary signa...

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書誌詳細
出版年:Entropy (Basel)
主要な著者: Hockenberry, Adam J., Wilke, Claus O.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818970/
https://ncbi.nlm.nih.gov/pubmed/31662602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/e21101000
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