PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α

BACKGROUND: Colorectal cancer (CRC) remains the fourth most common cause of cancer-related mortality worldwide. We aimed to identify key molecules and signalling pathways mediating CRC growth and metastasis. Polypyrimidine tract-binding protein 3 (PTBP3) is a member of PTB family. A prooncogenic rol...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Hou, Pingfu, Chen, Fang, Yong, Hongmei, Lin, Tian, Li, Jingjing, Pan, Yu, Jiang, Tao, Li, Minle, Chen, Yansu, Song, Jun, Zheng, Junnian, Bai, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622005/
https://ncbi.nlm.nih.gov/pubmed/31291975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1312-y
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