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LINC00460/DHX9/IGF2BP2 complex promotes colorectal cancer proliferation and metastasis by mediating HMGA1 mRNA stability depending on m6A modification

BACKGROUND: Increasing studies have shown that long noncoding RNAs (lncRNAs) are pivotal regulators participating in carcinogenic progression and tumor metastasis in colorectal cancer (CRC). Although lncRNA long intergenic noncoding RNA 460 (LINC00460) has been reported in CRC, the role and molecula...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Hou, Pingfu, Meng, Sen, Li, Minle, Lin, Tian, Chu, Sufang, Li, Zhongwei, Zheng, Junnian, Gu, Yuming, Bai, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851923/
https://ncbi.nlm.nih.gov/pubmed/33526059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01857-2
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