LINC00460/DHX9/IGF2BP2 complex promotes colorectal cancer proliferation and metastasis by mediating HMGA1 mRNA stability depending on m6A modification

BACKGROUND: Increasing studies have shown that long noncoding RNAs (lncRNAs) are pivotal regulators participating in carcinogenic progression and tumor metastasis in colorectal cancer (CRC). Although lncRNA long intergenic noncoding RNA 460 (LINC00460) has been reported in CRC, the role and molecula...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Hou, Pingfu, Meng, Sen, Li, Minle, Lin, Tian, Chu, Sufang, Li, Zhongwei, Zheng, Junnian, Gu, Yuming, Bai, Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851923/
https://ncbi.nlm.nih.gov/pubmed/33526059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01857-2
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