A Polymorphic Microsatellite Repeat within the ECE-1c Promoter Is Involved in Transcriptional Start Site Determination, Human Evolution, and Alzheimer's Disease

Genetic factors strongly contribute to the pathogenesis of sporadic Alzheimer's disease (AD). Nevertheless, genome-wide association studies only yielded single nucleotide polymorphism loci of moderate importance. In contrast, microsatellite repeats are functionally less characterized structures...

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Pubblicato in:J Neurosci
Autori principali: Li, Yaosi, Seidel, Kerstin, Marschall, Peter, Klein, Michael, Hope, Antonia, Schacherl, Jens, Schmitz, Jennifer, Menk, Mario, Schefe, Jan H., Reinemund, Jana, Hugel, Rebecca, Walden, Peter, Schlosser, Andreas, Volkmer, Rudolf, Schimkus, Julia, Kölsch, Heike, Maier, Wolfgang, Kornhuber, Johannes, Frölich, Lutz, Klare, Sabrina, Kirsch, Sebastian, Schmerbach, Kristin, Scheele, Sylvia, Grittner, Ulrike, Zollmann, Frank, Goldin-Lang, Petra, Peters, Oliver, Kintscher, Ulrich, Unger, Thomas, Funke-Kaiser, Heiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621774/
https://ncbi.nlm.nih.gov/pubmed/23175834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2636-12.2012
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