A Polymorphic Microsatellite Repeat within the ECE-1c Promoter Is Involved in Transcriptional Start Site Determination, Human Evolution, and Alzheimer's Disease

Genetic factors strongly contribute to the pathogenesis of sporadic Alzheimer's disease (AD). Nevertheless, genome-wide association studies only yielded single nucleotide polymorphism loci of moderate importance. In contrast, microsatellite repeats are functionally less characterized structures...

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Publicado no:J Neurosci
Main Authors: Li, Yaosi, Seidel, Kerstin, Marschall, Peter, Klein, Michael, Hope, Antonia, Schacherl, Jens, Schmitz, Jennifer, Menk, Mario, Schefe, Jan H., Reinemund, Jana, Hugel, Rebecca, Walden, Peter, Schlosser, Andreas, Volkmer, Rudolf, Schimkus, Julia, Kölsch, Heike, Maier, Wolfgang, Kornhuber, Johannes, Frölich, Lutz, Klare, Sabrina, Kirsch, Sebastian, Schmerbach, Kristin, Scheele, Sylvia, Grittner, Ulrike, Zollmann, Frank, Goldin-Lang, Petra, Peters, Oliver, Kintscher, Ulrich, Unger, Thomas, Funke-Kaiser, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621774/
https://ncbi.nlm.nih.gov/pubmed/23175834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2636-12.2012
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