Development of Experimental Autoimmune Encephalomyelitis Critically Depends on CD137 Ligand Signaling

Multiple sclerosis (MS) is a degenerative autoimmune disease of the CNS. Experimental autoimmune encephalomyelitis (EAE) is a commonly used murine model for MS. Here we report that CD137 ligand (CD137L, 4-1BB ligand, TNFS9), a member of the TNF superfamily, is critical for the development of EAE. EA...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Martínez Gómez, Julia M., Croxford, J. Ludovic, Yeo, Kim Pin, Angeli, Véronique, Schwarz, Herbert, Gasser, Stephan
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2012
Fag:
Brief Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621746/
https://ncbi.nlm.nih.gov/pubmed/23238738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2473-12.2012
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