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Development of Experimental Autoimmune Encephalomyelitis Critically Depends on CD137 Ligand Signaling
Multiple sclerosis (MS) is a degenerative autoimmune disease of the CNS. Experimental autoimmune encephalomyelitis (EAE) is a commonly used murine model for MS. Here we report that CD137 ligand (CD137L, 4-1BB ligand, TNFS9), a member of the TNF superfamily, is critical for the development of EAE. EA...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6621746/ https://ncbi.nlm.nih.gov/pubmed/23238738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2473-12.2012 |
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