Sulfatase 1 Promotes the Motor Neuron-to-Oligodendrocyte Fate Switch by Activating Shh Signaling in Olig2 Progenitors of the Embryonic Ventral Spinal Cord

In the developing ventral spinal cord, motor neurons (MNs) and oligodendrocyte precursor cells (OPCs) are sequentially generated from a common pool of neural progenitors included in the so-called pMN domain characterized by Olig2 expression. Here, we establish that the secreted Sulfatase 1 (Sulf1) i...

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Опубликовано в: :J Neurosci
Главные авторы: Touahri, Yacine, Escalas, Nathalie, Benazeraf, Bertrand, Cochard, Philippe, Danesin, Cathy, Soula, Cathy
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621745/
https://ncbi.nlm.nih.gov/pubmed/23238718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3553-12.2012
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