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Sulfatase 1 Promotes the Motor Neuron-to-Oligodendrocyte Fate Switch by Activating Shh Signaling in Olig2 Progenitors of the Embryonic Ventral Spinal Cord
In the developing ventral spinal cord, motor neurons (MNs) and oligodendrocyte precursor cells (OPCs) are sequentially generated from a common pool of neural progenitors included in the so-called pMN domain characterized by Olig2 expression. Here, we establish that the secreted Sulfatase 1 (Sulf1) i...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6621745/ https://ncbi.nlm.nih.gov/pubmed/23238718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3553-12.2012 |
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