Mrp14 Deficiency Ameliorates Amyloid β Burden by Increasing Microglial Phagocytosis and Modulation of Amyloid Precursor Protein Processing

Neuroinflammation plays a fundamental role in the pathogenesis of Alzheimer's disease (AD), resulting in the extensive activation of microglial and astroglial cells. Here we describe the role of myeloid-related protein Mrp14, a recently described amplifier of inflammation, in Alzheimer's d...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kummer, Markus P., Vogl, Thomas, Axt, Daisy, Griep, Angelika, Vieira-Saecker, Ana, Jessen, Frank, Gelpi, Ellen, Roth, Johannes, Heneka, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621649/
https://ncbi.nlm.nih.gov/pubmed/23223301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1504-12.2012
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